1.05: Christian McCaffrey
2.06: Chase Brown
3.05: George Pickens
4.06: Zay Flowers
5.05: Colston Loveland
6.06: Jadarian Price
7.05: Christian Watson
8.06: Rico Dowdle
9.05: Dak Prescott
10.06: Jacory Croskey-Merritt

In a 10-man league, the middle rounds are dynamite, because you're almost guaranteed to get an elite RB in the 2nd round as your RB1 or RB2. Pairing CMC with Chase Brown is a real possibility, and you're not sacrificing at the WR position. In 10-man leagues, QB and TE are slightly more valuable, so I make sure not to punt completely. Colston Loveland or Tyler Warren in the early 5th is great, and stacking Dak with Pickens is an awesome option as well.

1.06: Jaxon Smith-Njigba
2.05: Omarion Hampton
3.06: Malik Nabers
4.05: Javonte Williams
5.06: Jaylen Waddle
6.05: Davante Adams
7.06: Tucker Kraft
8.05: Tony Pollard
9.06: J.K. Dobbins
10.05: Trevor Lawrence

Loading up on WR and RB early is always going to feel good in a 10-man league. Omarion Hampton, Javonte Williams, JSN, and Malik Nabers gives you one heck of a foundation. I loaded up on WR depth in the middle rounds based on the way the draft fell, but I wouldn't hate adding more RB depth as well. With how deep the QB position is, you still don't necessarily need to spend up, unless your league-mates are over-drafting them and stashing multiple QBs on their benches.

1.07: James Cook
2.04: Brock Bowers
3.07: Kyren Williams
4.04: DeVonta Smith
5.07: Jaylen Waddle
6.04: Joe Burrow
7.07: Christian Watson
8.04: Parker Washington
9.07: Rico Dowdle
10.04: Jordan Addison

I wanted to throw in one option with an elite TE and higher pick QB to show what's possible. I'm more willing to spend up on Brock Bowers because elite positional dominance matters more when rosters are deeper and more stacked at WR/RB. Even with a 6th round pick on Burrow and a 2nd round pick on Bowers, you don't sacrifice significantly at WR or RB and still feel pretty good about your flex spots.