Derrick Henry finishes the week as the RB1

Remember what happened last year? Derrick Henry came out on SNF and gave us a 169-yard, 2 touchdown performance against the Bills, good enough for RB1 on the week. The Colts had a so-so defense against the rush last year, but Henry has proven time and again that he is matchup proof. Watch out for whether the new coaching staff looks to get him more involved in the receiving game this year.

Tyler Warren Gets 10+ Targets

It only happened once last season, but now that he's had a full year in the Colts' system, Tyler Warren should be the focal point of this offense. Warren came out the gates hot in 2025 with 9 targets and 7 catches for 76 yards against Miami in Week 1, and it wouldn't surprise me to see him do something similar this year and lock himself in as a top 4 TE to roster this year.

Chris Bell Finishes the Week as a WR2

This one is out there, but fortune favors the bold. The matchup for Miami is genuinely great; the Raiders don't project to have a good defense, and with Brock Bowers missing time, I actually think the Dolphins could have the slight edge in this game. Bell was named a week 1 starter alongside fellow rookie Caleb Douglas. If Malik Willis can be even somewhat serviceable for this team, Bell could be a valuable bench stash in fantasy and someone you could eventually play in your flex. I'd still leave him on your bench, but it wouldn't surprise me to see him as a heavy Week 2 waiver wire pickup.